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bornontheblue

Corona Virus - How bad is it going to be?

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2 hours ago, mugtang said:

We phucked up a lot with this pandemic.  But...this is good news!  We always find a way to kick ass.  :USFlag:

 

 

Not so fast. I am watching the Blue Jays play the Rangers in a full stadium, and not a mask to be seen on a fan, LOL 

 

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Amazing.

https://www.europeanpharmaceuticalreview.com/news/141892/novel-hiv-vaccine-approach-shows-promise-in-landmark-first-in-human-trial/ 

A novel vaccine approach for the prevention of HIV has shown promise in Phase I trials, reported IAVI and Scripps Research. According to the organisations, the vaccine successfully stimulated the production of the rare immune cells needed to generate antibodies against HIV in 97 percent of participants.

The vaccine is being developed to act as an immune primer, to trigger the activation of naïve B cells via a process called germline-targeting, as the first stage in a multi-step vaccine regimen to elicit the production of many different types of broadly neutralizing antibodies (bnAbs). Stimulating the production of bnAbs has been pursued as a holy grail in HIV for decades. It is hoped that these specialised blood proteins could attach to HIV surface proteins called spikes, which allow the virus to enter human cells, and disable them via a difficult-to-access regions that does not vary much from strain to strain...

...As a next step, the collaborators are partnering with the biotechnology company Moderna to develop and test an mRNA-based vaccine that harnesses the approach to produce the same beneficial immune cells. According to the team, using mRNA technology could significantly accelerate the pace of HIV vaccine development, as it did with vaccines for COVID-19.

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23 hours ago, Del Scorcho said:

Remember how people were yammering about how social distancing, mask wearing businesses shutting down were going to result in mass suicides. 

According to the NHCS (National Center for Health Statistics) and the NVSS (National Vital Statistics System). Suicides were actually lower in 2020 than they’ve been in the previous four years.

  • 2020: 44,834
  • 2019: 47,511
  • 2018: 48,344
  • 2017: 47,173
  • 2016: 44,965

 

 

 

 

While I applaud the fact that suicides are down, this doesn't mean that mental health generally isn't much worse as a result of telling everyone to stay inside for a year. I'll be interested to see how it shakes out in 2021. I have a massive package. Lockdowns generally don't help overall mental health and well being. 

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16 hours ago, bornontheblue said:

Not so fast. I am watching the Blue Jays play the Rangers in a full stadium, and not a mask to be seen on a fan, LOL 

 

Negative.  Game was on local TV, was the lead story on the local news, and also the main story this morning on local radio.  mask usage was mixed.

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California to lift all but a few statewide restrictions (the ones to remain relate to conferences and large indoor gatherings) on June 15. This is assuming that vaccines are available for anyone over 16 by then and that hospitalization rates continue to trend downward. 

I will be interested in seeing if any local municipalities or institutions like colleges continue with tighter restrictions even after the state-level restrictions are gone. My county is not one of only two counties in the most restrictive tier, which is really +++++ing annoying. Especially since it might be due to a backlog of tests and not an actual accurate reflection of the current infection rate.

I hope that if we continue to see vax rates trend up and supply continue to flow into the state, and hospitalization numbers stay low, that we can get the restrictions off even earlier than that. 

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42 minutes ago, thelawlorfaithful said:

Mind blowing what we were facing a year ago. Operation Warp Speed indeed.

 

To better clarify:

  1. Germany funded Pfizer's development of the vaccine, not the US.
  2. The mRNA technology already existed, and is owned by Pfizer's parent company, BioNTech (another German firm), who supplied it to Pfizer.
  3. All the US did was to commit to buying the vaccine, who's development and production was funded by Germany.
  4. No one had to build new factories.
  5. Moderna's expedited rollout was due to outsourcing production to manufacturers who already had the infrastructure in place.

Don't get me wrong - credit to the last administration for prioritizing the rapid roll out to state and local agencies. Imagine how much more ahead of the game we would have been if they hadn't ignored the 'last mile' of vaccine distribution channels or taken testing (and the virus) as seriously early on as they did the trailing end process of developing a vaccine. :hmmm:

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7 minutes ago, TheSanDiegan said:

To better clarify:

  1. Germany funded Pfizer's development of the vaccine, not the US.
  2. The mRNA technology already existed, and is owned by Pfizer's parent company, BioNTech (another German firm), who supplied it to Pfizer.
  3. All the US did was to commit to buying the vaccine, who's development and production was funded by Germany.
  4. No one had to build new factories.
  5. Moderna's expedited rollout was due to outsourcing production to manufacturers who already had the infrastructure in place.

Don't get me wrong - credit to the last administration for prioritizing the rapid roll out to state and local agencies. Imagine how much more ahead of the game we would have been if they hadn't ignored the 'last mile' of vaccine distribution channels or taken testing (and the virus) as seriously early on as they did the trailing end process of developing a vaccine. :hmmm:

2 billion > 445 million.  

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Today's Bob-like quote of the day:

 

 

“I would ask you — because I’m addicted to truth, logic and common sense, and my common sense meter would demand the answer to — why weren’t we shut down for COVID-1 through -18?  There was a COVID-1, and there was a COVID-2, -3, -4, -5, -6, -7, -8, -9, -10, -11, -12, -13, -14, -15, -16, -17, -18. COVID-1 through -18 didn’t shut anything down, but whoa, COVID-19, even though it’s 99.8 percent survivable. "

 

- Ted Nugent

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13 minutes ago, RSF said:

Today's Bob-like quote of the day:

 

 

“I would ask you — because I’m addicted to truth, logic and common sense, and my common sense meter would demand the answer to — why weren’t we shut down for COVID-1 through -18?  There was a COVID-1, and there was a COVID-2, -3, -4, -5, -6, -7, -8, -9, -10, -11, -12, -13, -14, -15, -16, -17, -18. COVID-1 through -18 didn’t shut anything down, but whoa, COVID-19, even though it’s 99.8 percent survivable. "

 

- Ted Nugent

Let it be known, today and forever more: Don't take medical advice from aging guitarists. ... Unless it is Keith Richards' secret to immortality.

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Just now, NVGiant said:

Let it be known, today and forever more: Don't take medical advice from aging guitarists. ... Unless it is Keith Richards' secret to immortality.

Yeah was going to say that Keith Richards is the only one whose advice is worth seeking.

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5 minutes ago, NVGiant said:

Let it be known, today and forever more: Don't take medical advice from aging guitarists. ... Unless it is Keith Richards' secret to immortality.

Yup...in a nuclear war only cockroaches and Keith will survive.

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6 minutes ago, RSF said:

Yup...in a nuclear war only cockroaches and Keith will survive.

If Moderna and Pfizer were really smart, they'd just use Richards' DNA as a vaccine. Cure the world of all disease. 

The One Where Estelle Dies Episode 15 GIF by Friends

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